TRIBRISSEN™

Description: Trimethoprim and Sulfadiazine Powder

Contains: Trimethoprim and Sulfadiazine

Formulation: Powder for incorporation into fish feed. Contains 66.7g trimethoprim /kg and 333.3g sulfadiazine /kg.

Pharmacologic Properties: Tribrissen* is active against a wide spectrum of bacterial pathogens, both gram-negative and gram-positive. It is bactericidal against susceptible strains and is often effective against sulfonamide-resistant organisms. Proven effective against the following pathogens:

  • Vibrio spp
  • Pasteurella species
  • Streptococcus species
  • Yersinia ruckeri
  • Aeromonas salmponicida
  • Photobacterium piscicida

In vitro, sulfadiazine is usually only bacteriostatic. Tribrissen* imposes a sequential double blockade on bacterial metabolism. This deprives bacteria of nucleic acids and proteins essential for survival and multiplication and produces a high level of antibacterial activity, which is usually bactericidal.

Target Species: Salmonids: including Atlantic salmon, Pacific salmon, brown trout, brook trout and rainbow trout

Dosage and Administration: The recommended dose is 30 mg of combined active ingredients (75mg powder) per kg bodyweight of fish daily for a period of 7-10 days. Tribrissen* 40% Powder is intended solely for administration in feed. It may be incorporated into the feed at time of manufacture or mixed with manufactured feed prior to feeding.

Withdrawal time: **

Product Presentation:

  • 1kg polypropylene tub
  • 3.75 kg tinplate container
  • 20kg drum

Special Requirements for Use: As designated by local regulatory authorities.

Storage Conditions: Store in original container in a dry place. Protect from light. Re-close partly used container.

Shelf-life: See local package insert for details.

Label Indications: For the treatment of infections of fish caused by organisms susceptible to trimethoprim/sulfadiazine.

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This website contains information on veterinary pharmaceutical and biological products based on international registration dossiers. The site may refer to products that are either not available in your country or are marketed under a different tradename. In addition, the safety and efficacy data and the withholding periods for a specific product may be different depending on local regulations. Please consult your veterinarian for further information.


* In some markets approved for all susceptible bacteria
**Approved species, claims and withdrawal times may vary from country to country. Please check your local package insert or contact your local MSD Animal Health representative for more details.

NOTE: Specific product details of indications, registration license status, and trademarks, etc. may vary from country to country. Users should check the license status, local label and/or data sheet for exact specifications of usage or contact the local Schering-Plough Animal Health representative