Slice™

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Slice™



0.2% Emamectin Benzoate Medicated Feed Premix

For the treatment and prevention at group level of infestations of all parasitic stages of sea lice (Lepeophtheirus sp. and Caligus sp.) on Atlantic salmon (Salmo salar) ranging in size from smolts in freshwater (just prior to transfer to seawater) to market weight fish in seawater.

Key Benefits

  • High level efficacy: SLICE* kills all parasitic stages (motile and non-motile) of sea lice.

  • Duration of efficacy: SLICE* kills all stages of sea lice including gravid adult females for up to 10 weeks.

  • Effective under a wide range of environmental conditions, i.e. water temperatures of 5°-15°C in both freshwater and seawater.

  • Well tolerated: SLICE* was well tolerated at more than 3x the dose rate with no mortality or significant reduction in feeding associated with treatment.

  • Well tolerated when administered to smolts prior to transfer to sea.

Dosage and Administration

Medicated feed is prepared by coating SLICE* Premix onto the surface of non-medicated fish feed pellets.

Administer at 50μg active/kg fish biomass/day for seven consecutive days. The suggested feeding rate is 0.5% fish biomass per day.

Withdrawal time: **

Product Presentation:
SLICE* Premix is supplied in 2.5 kg sachets containing 5 g of emamectin benzoate (0.2% w/w).

Pharmacologic Properties:
Emamectin is an avermectin compound derived synthetically from avermectins which are produced by fermentation of the soil organism Streptomyces avermitilis. The benzoate salt confers stability on the molecule. When fed to fish emamectin benzoate is absorbed from the gut and distributed to the tissue of the fish. When sea lice feed on tissues of treated fish, emamectin is taken up into the tissues of the louse.  Emamectin then binds to ion channels of nerve cells and disrupts transmission of nerve impulses, which results in paralysis and death of the parasite. Emamectin benzoate is excreted slowly by fish and metabolized to inactive compounds, resulting in long-lasting protection.

* SLICE(R) is the property of Intervet International B.V. or affiliated companies or licensors and is protected by copyrights, trademark and other intellectual property laws.

** NOTE: Specific product details of indications, registration license status and trademarks, etc. may vary from country to country.  Users should check the license status, local label and/or data sheet for exact specifications of usage or contact their local Intervet/Schering-Plough Animal Health representative.