Norvax® Vibrio mono




Inactivated vaccine against vibriosis disease for immersion vaccination in yellowtail.

Inactivated strain of Listonella (Vibrio) anguillarum serovar O1.

Water-based suspension for immersion.

For active immunization of susceptible fish species to aid in the protection against vibriosis disease caused by Listonella (Vibrio) anguillarum.

The preferred method for vaccination is by immersion of 1- to 3.4-gram fish.

0.5 litre of vaccine is mixed with 4.5 litres of seawater. Using a knot less hand net, immerse 1.85 kg of fish into this vaccine solution for 30 seconds. Prepare a new vaccine solution after having vaccinated 5.55 kg of fish. Ensure good oxygenation or aeration during immersion vaccination.

Nil. (National regulations should be observed).

Norvax® Vibrio mono is available in 500-ml PET bottles.

Store and transport between 2 and 10°C. Do not freeze. Once opened, bottles should be used the same day. Don't use after the expiry date.


Vaccination is recommended for fish at or above 35 grams. The water temperature at vaccination should be at or below 15°C. Fish should be withheld from feed for 1-2 days before vaccination. Fish should be anaesthetised according to veterinary recommendations. Start feeding, at the earliest, 12 hours after vaccination. Only healthy fish should be vaccinated. Do not use in breeding stock. No information is available on the safety and efficacy from the concurrent use of this vaccine with any other. It is therefore recommended that no other vaccines should be administered within 14 days before or after vaccination with this product. Shake well before use. Sterile injection equipment should be used. At least 500 degree days are recommended from vaccination to potential exposure to furunculosis, vibriosis, coldwater vibriosis, wound disease or IPN.

When undesirable effects occur, they are normally seen in the abdominal cavity. Vaccinated animals normally show very slight to moderate adhesions between viscera or between viscera and the abdominal wall. The eventual adhesions may be removed manually and are thus not severe. Occasionally, vaccinated populations may show adhesions between greater parts of the abdominal organs, granulomas and/or more massive pigmentation. Such lesions are typically seen in < 10% of the treated animals.

To the user:
This product contains mineral oil. Accidental injection/self injection may result in severe pain and swelling, particularly if injected into a joint or finger, and in rare cases could result in the loss of the affected finger if prompt medical attention is not given. If you are accidentally injected with this product, seek prompt medical advice even if only a very small amount is injected and take the package insert with you. If pain persists for more than 12 hours after medical examination, seek medical advice again.
To the physician:
This product contains mineral oil. Even if small amounts have been injected, accidental injection with this product can cause intense swelling, which may, for example, result in ischemic necrosis and even the loss of a digit. Expert, PROMPT, surgical attention is required and may necessitate early incision and irrigation of the injected area, especially where there is involvement of finger pulp or tendon.